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September 10, 2025Discover OncologyOpen Access

Exploring the prognostic value and immune landscape of EGLN1 in colorectal cancer: insights from bioinformatics analysis

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Authors

XCX.P. ChenCHChiung‐Yao HuangYLYulin Liao

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Overview

Analysis reveals EGLN1 as a potential biomarker for colorectal cancer, influencing patient survival and immune landscape.

Key Points

  • EGLN1 is identified as a promising biomarker in colorectal cancer, indicating its potential as a tumor suppressor.
  • Significant decrease in EGLN1 levels in tumors correlates with worse patient outcomes, suggesting its role in prognosis.
  • Gene set enrichment analysis reveals EGLN1's involvement in key biological pathways related to cancer progression.
  • The immune landscape analysis shows EGLN1's impact on immune infiltration and immune checkpoint molecules.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d64797e92https://doi.org/10.1007/s12672-025-03331-3
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