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September 10, 2025Journal of Diabetes ResearchOpen Access

Decreased Serum Adipose Triglyceride Lipase Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes

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Authors

YWYing WangTLTong‐Tong LiuNLNan Li

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Overview

Assessment identifies serum ATGL as a potential biomarker for diabetic kidney disease, suggesting its role in lipid metabolism.

Key Points

  • Lower serum ATGL levels were significantly correlated with impaired renal function in patients with type 2 diabetes.
  • The study noted a positive correlation between serum ATGL levels and estimated glomerular filtration rates (eGFR), underlining its protective role in kidney function.
  • Receiver operating characteristic analysis indicated that incorporating ATGL levels improved the sensitivity of traditional kidney disease markers.
  • Logistic regression analyses confirmed that serum ATGL is a protective factor against diabetic kidney disease development, adjusting for potential confounders.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d647978fchttps://doi.org/10.1155/jdr/9987648
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