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September 10, 2025American Journal of PediatricsOpen Access

Serum Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Babies with Perinatal Asphyxia in Abia State, South-East Nigeria

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Authors

SIStella IjeomaNONneka Chioma OkoronkwoFEFelicia U. Eke

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Overview

Cross-sectional study finds serum NGAL significantly detects acute kidney injury in neonates, highlighting its clinical relevance.

Key Points

  • Serum NGAL levels are elevated in acute kidney injury cases among asphyxiated neonates.
  • Increased severity of perinatal asphyxia correlates with higher serum NGAL concentrations, with p < 0.05.
  • A serum NGAL cut-off of 270 ng/ml effectively identifies AKI, achieving a sensitivity of 99.3%.
  • Study conducted in the Newborn Special Care Unit, suggesting serum NGAL measurement for early AKI detection.

Cite This Study

Ijeoma et al. (2025) studied this question.

synapsesocial.com/papers/68c23f63b210217d647970fbhttps://doi.org/10.11648/j.ajp.20251103.17
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