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September 10, 2025The Clinical Respiratory JournalOpen Access

Association of T‐Cell Profiles With Disease Severity, Drug‐Induced Liver Injury, and Treatment Completion in Tuberculosis

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Authors

YHYifan HeXZXubin ZhengZDZihan Dang

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Overview

Analysis reveals T-cell profiles affecting disease severity and drug-induced liver injury in tuberculosis.

Key Points

  • Specific T-cell phenotypes correlate with tuberculosis severity, suggesting immune markers for monitoring.
  • Six distinct T-cell subsets, notably expressing PD-L1, were linked with disease progression in tuberculosis.
  • Peripheral blood mononuclear cells from 40 tuberculosis patients were analyzed using flow cytometry for T-cell profiles.
  • Findings may enhance understanding of treatment outcomes and drug-induced liver injury in tuberculosis cases.

Cite This Study

He et al. (2025) studied this question.

synapsesocial.com/papers/68c23f63b210217d64796c5ehttps://doi.org/10.1111/crj.70114
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