Retrospective analysis shows lymph node ratio and tumor characteristics impact survival in colorectal SRCC, suggesting enhanced predictive modeling.
Key Points
High lymph node ratio and presence of tumor deposits are linked to poorer cancer-specific survival in colorectal signet-ring cell carcinoma.
Multivariate analysis identified T stage, M stage, tumor deposits, CEA, chemotherapy, and lymph node ratio as independent prognostic factors for outcome.
Analysis revealed that a nomogram model combining lymph node ratio, tumor deposits, and perineural invasion had superior predictive performance.
This combined variable significantly improved the ability to predict overall survival compared to traditional staging metrics.