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September 10, 2025npj Biofilms and MicrobiomesOpen Access

Infant gut microbiota and SCFAs mediate the association between early-life human milk microbiota and neurodevelopment

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Authors

SWSimou WuWJWen JiaJLJinxing Li

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Overview

Cohort study investigates the roles of human milk microbiota and short-chain fatty acids in neurodevelopment.

Key Points

  • HMM influences IGM and neurodevelopment through SCFAs, suggesting a direct connection.
  • On day 30, SCFAs mediate the association between IGM and neurodevelopment, indicating their importance.
  • Breast milk and infant feces samples were analyzed for microbiota sequencing and SCFAs quantification.
  • Findings indicate that early intervention in mother-infant microecology may prevent neurodysplasia.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68c23f63b210217d64796353https://doi.org/10.1038/s41522-025-00790-y
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