September 10, 2025AntibioticsOpen Access

An OSMAC Strategy for the Production of Antimicrobial Compounds by the Amazonian Fungi Talaromyces pinophilus CCM-UEA-F0414 and Penicillium paxilli CCM-UEA-F0591

View Full Paper

Ask AI

Bookmark

Extracts from Amazonian fungi showed significant antimicrobial activity, with MICs from 78 to 5000 µg/mL.
Chemical analyses confirmed phenolic compounds such as caffeic and chlorogenic acids in the fungi extracts.
Cultivating strains in different media markedly influenced both the metabolite profiles and the antimicrobial efficacy.
The OSMAC strategy harnesses the biosynthetic potential of fungal biodiversity for discovering new antimicrobial agents.

Authors

CACleudiane Pereira de AndradeUniversidade do Estado do Amazonas CLCaroline Dutra LacerdaUniversidade de São Paulo RVR. ValenteEscola Superior de Ciências da Saúde

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

This study demonstrates enhanced antimicrobial activity in Talaromyces pinophilus and Penicillium paxilli, suggesting the OSMAC approach optimizes secondary metabolite production.

Cite This Study

Andrade et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d64795d97 https://doi.org/10.3390/antibiotics14080756

View Full Paper

Ask AI

Bookmark

Implication

This study demonstrates enhanced antimicrobial activity in Talaromyces pinophilus and Penicillium paxilli, suggesting the OSMAC approach optimizes secondary metabolite production.

An OSMAC Strategy for the Production of Antimicrobial Compounds by the Amazonian Fungi Talaromyces pinophilus CCM-UEA-F0414 and Penicillium paxilli CCM-UEA-F0591

Key Points

Discussion

Implication

Cite This Study

An OSMAC Strategy for the Production of Antimicrobial Compounds by the Amazonian Fungi Talaromyces pinophilus CCM-UEA-F0414 and Penicillium paxilli CCM-UEA-F0591

Key Points

Discussion

Implication

Cite This Study