Antioxidant and Anti-inflammatory Roles of Yacon Leaf Extract (Smallanthus sonchifolius Poepp. H. Rob.) Mitigated Diabetes in a Rat Model

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This observational analysis shows yacon leaf extract improved insulin levels in diabetic rats, indicating its antidiabetic potential.

Yacon leaf extract significantly reduced serum glucose levels and increased insulin levels in Wistar rats.
After 21 days of treatment, pancreatic catalase increased and malondialdehyde levels decreased, indicating reduced oxidative stress.
Liquid chromatography was used to analyze Yacon leaf extract compounds, revealing key antioxidants that contribute to its effects.
The findings suggest possible therapeutic applications for yacon leaf extract in managing diabetes and pancreatic inflammation.

Widowati et al. (2025) studied this question.

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