September 10, 2025Epidemiology

Time-related bias when studying perinatal complications after maternal injuries: Application to maternal injuries and preterm birth

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Maternal injuries correlate with an increased risk of preterm birth, especially in later trimesters.
Injuries during the third trimester showed a counterintuitive association of reduced preterm birth risk in some analyses.
Rigorous methodologies reveal time-related biases often underestimate true associations in maternal injury studies.
Using time-varying analysis produced more accurate estimates than traditional time-fixed methods.

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Retrospective cohort study assesses increased preterm birth risk from maternal injuries, highlighting time-related biases.

Ahmed et al. (2025) studied this question.

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