September 10, 2025Journal of CancerOpen Access

Differential diagnosis of benign and malignant ovarian tumors with combined tumor and systemic inflammation-related markers

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Authors

DSDan Song TLTingting LiuNorthwestern University CHChao HanChangzhi Medical College

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Implication

Analysis identifies key tumor markers and inflammation-related indicators for diagnosing epithelial ovarian cancer, suggesting improved clinical strategies.

Key Points

Preoperative tumor and inflammatory markers improve early detection of epithelial ovarian cancer.
CA125 and HE4 levels were significantly higher in ovarian cancer patients compared to benign cases (P < 0.001).
The combination model comprising CA125, HE4, PLR, MLR, and SII showed the highest diagnostic accuracy with an AUC of 0.951.
Sensitivity of the best-performing model was 84.66%, indicating strong efficacy for clinical diagnosis.

Cite This Study

Song et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d647950fb https://doi.org/10.7150/jca.112768

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Implication

Analysis identifies key tumor markers and inflammation-related indicators for diagnosing epithelial ovarian cancer, suggesting improved clinical strategies.

Differential diagnosis of benign and malignant ovarian tumors with combined tumor and systemic inflammation-related markers

Discussion

Member takes

Implication

Key Points

Cite This Study

Differential diagnosis of benign and malignant ovarian tumors with combined tumor and systemic inflammation-related markers

Discussion

Member takes

Implication

Key Points

Cite This Study

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