September 10, 2025Journal of Diabetes ResearchOpen Access

Mechanistic Insights Into Qidan Yixin Decoction for Diabetic Cardiomyopathy via Macrophage Polarization

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Discussion

Network pharmacology identifies key pathways and active ingredients in diabetic cardiomyopathy treatment, suggesting therapeutic potential.

Qidan Yixin decoction improves cardiac function in diabetic cardiomyopathy, specifically by moderating macrophage polarization.
Core targets PGK1 and LDHA were identified through machine learning techniques, key components in the therapeutic mechanism.
Analysis revealed that HIF-1 signaling pathway modulation contributes significantly to DCM treatment effectiveness.
Animal experiments validated that Qidan Yixin decoction suppresses M1 macrophage polarization, enhancing overall cardiac performance.

Liu et al. (2025) studied this question.

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September 10, 2025Journal of Diabetes ResearchOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Network pharmacology identifies key pathways and active ingredients in diabetic cardiomyopathy treatment, suggesting therapeutic potential.

Qidan Yixin decoction improves cardiac function in diabetic cardiomyopathy, specifically by moderating macrophage polarization.
Core targets PGK1 and LDHA were identified through machine learning techniques, key components in the therapeutic mechanism.
Analysis revealed that HIF-1 signaling pathway modulation contributes significantly to DCM treatment effectiveness.
Animal experiments validated that Qidan Yixin decoction suppresses M1 macrophage polarization, enhancing overall cardiac performance.

Liu et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark