A study on gamma-glutamyl transferase and C-reactive protein levels in type 2 diabetes mellitus patients and their correlation with glycosylated hemoglobin levels

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Observational study evaluated GGT and CRP levels in T2DM patients, highlighting their correlation with HbA1c.

A strong positive correlation between GGT and HbA1c was found (r=0.900, p<0.001), indicating GGT's role as a glycemic control marker.
Mean serum levels of GGT, CRP, and HbA1c were 41.51±24.8 mg/dl, 11.14±11.4 mg/dl, and 7.83±1.59 mmol/l respectively.
CRP also showed a weaker yet significant correlation with HbA1c (r=0.047, p=0.030), suggesting inflammation's impact on diabetes.
The findings support the potential utility of GGT as a biomarker for oxidative stress in type 2 diabetes management.

Sathvika et al. (2025) studied this question.

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