September 10, 2025European Journal of RadiologyOpen Access

Assessing internal carotid artery stenosis: Diagnostic Value of photon-counting detector CT angiography compared to Doppler ultrasound

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Authors

SRStephan RauUniversity of Freiburg CSChristoph StreckerUniversity of Freiburg MRMaximilian Frederik RusseUniversity of Freiburg

Discussion

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Implication

Observational analysis reveals high sensitivity and specificity for photon-counting detector CT angiography in assessing internal carotid artery stenosis, indicating its value compared to Doppler ultrasound.

Key Points

PCD-CTA achieved 93.8% sensitivity and 93.8% specificity for detecting significant ICA stenosis compared to CDUS.
Strong agreement was observed between PCD-CTA and CDUS, with a Spearman's rho of 0.951, confirming diagnostic accuracy.
Inter-reader reliability was moderate with Fleiss's kappa values of 0.56 for visual assessments and 0.53 for measurement-based grading.
Misclassification issues in cases with severe calcifications highlight the need for improved imaging techniques and analysis.

Cite This Study

Rau et al. (2025) studied this question.

synapsesocial.com/papers/68c23ed7b210217d647939ac https://doi.org/10.1016/j.ejrad.2025.112338

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