September 10, 2025PLoS ONEOpen Access

Predicting pulmonary function using thoracic deformity parameters in early onset scoliosis patients

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The study successfully predicts pulmonary function test values in early onset scoliosis patients using radiographic data.
Multiple linear regression models achieved significant predictive accuracy for %FVC and %FEV1, with R² values of 0.54 and 0.59 respectively.
Using a dataset of 47 patients, validated models demonstrated no significant differences in prediction error magnitudes.
Identifying key deformity parameters can guide clinical decisions and surgical treatments for early onset scoliosis.

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Retrospective analysis predicts pulmonary function values in early onset scoliosis patients, suggesting new clinical metrics.

Orbach et al. (2025) studied this question.

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