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September 10, 2025Tropical Journal of Natural Product ResearchOpen Access

Recent Strategies for Enhancing the Solubility and Dissolution of Poorly Water-Soluble Curcumin for Therapeutic Purposes and Beyond

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Authors

NLNguyen Le-PhucMNMinh N. NguyenQLQuoc‐Viet Le

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Overview

This review discusses approaches to enhance curcumin's dissolution and bioavailability for drug delivery, highlighting nanoparticle and bioconjugate systems.

Key Points

  • Curcumin's poor solubility limits its therapeutic potential, making effective delivery essential.
  • Advancements like nanoparticles and bioconjugates show promise in improving bioavailability and stability.
  • Techniques reviewed include particle size reduction and complexation, each with distinct advantages and limitations.
  • Future directions aim to address current challenges, enhancing the use of curcumin in effective therapeutics.

Cite This Study

Le-Phuc et al. (2025) studied this question.

synapsesocial.com/papers/68c23ed7b210217d647937ffhttps://doi.org/10.26538/tjnpr/v9i7.70
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