Research reveals strong antibacterial effects against Cutibacterium acnes in a rhizome extract, suggesting its potential for dermatological use.
Key Points
The extract exhibited a significant inhibition zone of 24.00 ± 1.73 mm against Cutibacterium acnes, demonstrating effective antibacterial properties.
HPLC analysis identified major phenolics such as 4-methoxycinnamyl p-coumarate, which showed superior antibacterial efficacy over Staphylococcus epidermidis.
Cytotoxicity testing confirmed that the extract is noncytotoxic to human dermal fibroblasts, ensuring safety for skin applications.
The study highlights the potential of the extract as a natural ingredient in skincare, offering solutions for managing microbial infections and inflammation.