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September 10, 2025EClinicalMedicineOpen Access

Examining the feasibility of a crisis-focused Cognitive Behaviour Therapy (CBT)–informed psychological intervention for inpatients experiencing psychosis (the CRISIS study): results from a pilot randomised controlled trial

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Authors

LWLisa WoodAMAnthony P. MorrisonMBMary Birken

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Overview

Pilot randomized controlled trial assessed the feasibility of crisis-focused cognitive behavioural therapy in inpatients with psychosis, highlighting recruitment and data collection challenges.

Key Points

  • A pilot RCT of crisis-focused cognitive behavioural therapy for psychosis showed feasibility with inpatient participants experiencing psychosis.
  • Recruitment reached 87% of the target sample size, with 52 participants randomized into intervention or usual treatment.
  • Follow-up data collection rates were 58% at 2 months and 60% at 6 months, falling below feasibility thresholds.
  • A larger fully powered trial is needed to evaluate effectiveness and cost-effectiveness of this intervention approach.

Cite This Study

Wood et al. (2025) studied this question.

synapsesocial.com/papers/68c23e94b210217d647931dfhttps://doi.org/10.1016/j.eclinm.2025.103380
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