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September 10, 2025Biomarkers in Medicine

Clinical efficacy of combined detection of serum procalcitonin and C-reactive protein in early differential diagnosis of bacterial and viral pneumonia and analysis of related inflammatory response mechanisms

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Authors

RYRong YuYTYan TangJHJing He

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Overview

Retrospective analysis identifies PCT and CRP as effective dual biomarkers in pneumonia, suggesting improved diagnostic accuracy.

Key Points

  • Combined measurement of procalcitonin and C-reactive protein significantly improves pneumonia diagnosis.
  • ROC analysis showed PCT+CRP achieved an AUC of 0.943, indicating high diagnostic accuracy.
  • Elevations in both markers were strong indicators of bacterial pneumonia severity and etiology.
  • This dual-biomarker strategy could enhance antimicrobial treatment decisions based on accurate differentiation.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68c23e94b210217d64792bd8https://doi.org/10.1080/17520363.2025.2538428
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