September 10, 2025PathogensOpen Access

Development of a Clostridium Perfringens Challenge Model in Broiler Chickens to Evaluate the Effects of Feed Additives

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The challenge model effectively highlights differences in gut health related to feed additives.
Significant differences in gut lesion scores were found between positive and negative control groups.
No clinical signs were observed in the negative control group or antibiotic-treated group.
The study demonstrates a reliable method to evaluate the effects of feed additives on broiler chicken health.

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Randomized trial established a challenge model for necrotic enteritis in broiler chickens, suggesting potential for feed additives assessment.

Kollár et al. (2025) studied this question.

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Randomized trial established a challenge model for necrotic enteritis in broiler chickens, suggesting potential for feed additives assessment.