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September 10, 2025Pulmonary CirculationOpen Access

Reassessment of the Current Iron Deficiency Definition in Pulmonary Hypertension

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Authors

ARAurelia E. ReiserMTMarkus ThierschGMGiovanni E. Mann

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Overview

Observational analysis identifies TFRI-ID as a significant prognostic marker in pulmonary hypertension, suggesting a need for updated definitions.

Key Points

  • TFRI-ID shows an association with higher NT-proBNP levels in pulmonary hypertension patients.
  • Ferritin-ID was met by 67% of patients, while TSAT-ID and TFRI-ID were 35% and 13%, respectively.
  • After adjusting for confounders, mean pulmonary arterial pressure showed no significant difference between TFRI-ID and non-ID groups.
  • Six-minute walk distances were significantly lower in TSAT-ID and TFRI-ID patients compared to non-ID.

Cite This Study

Reiser et al. (2025) studied this question.

synapsesocial.com/papers/68c23e94b210217d64792a02https://doi.org/10.1002/pul2.70142
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