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September 10, 2025The Anatolian Journal of CardiologyOpen Access

Association Between Triglyceride-Glucose Index and Prognosis of Patients with Hypertrophic Cardiomyopathy and Heart Failure with Preserved Ejection Fraction

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Authors

LLLei LiuYZYi ZhengHMHuihui Ma

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Overview

Observational analysis indicates higher triglyceride-glucose index reduces cardiovascular mortality in hypertrophic cardiomyopathy patients with preserved ejection fraction.

Key Points

  • A higher triglyceride-glucose index was associated with lower risks of all-cause mortality in patients with hypertrophic cardiomyopathy.
  • Multivariable Cox regression showed significant reductions in cardiovascular mortality with elevated triglyceride-glucose index quartiles.
  • No significant association was found between the triglyceride-glucose index and sudden cardiac death in these patients.
  • Mediation analyses suggested N-terminal pro-B-type natriuretic peptide mediates survival outcomes related to the triglyceride-glucose index.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c23e94b210217d647928f4https://doi.org/10.14744/anatoljcardiol.2025.5240
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