Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

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The engineered vascular structure demonstrates in vitro contraction in response to angiotensin II, improving functionality.
Bioink's dynamic covalent crosslinking allows an adjustable microenvironment for effective cell compartmentalization and vasculature formation.
The vascular network contributes significantly to blood perfusion in mouse hind limb ischemia models, enhancing healing.
Focal adhesion kinase pathway links bioink adaptability with vascular organization through integrin-mediated adhesion.

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This study reveals how bioink facilitates vascularization and cell compartmentalization, indicating a new approach for engineered tissues.

Chen et al. (2025) studied this question.

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This study reveals how bioink facilitates vascularization and cell compartmentalization, indicating a new approach for engineered tissues.