Evaluation of neutrophil gelatinase-associated lipocalin (NGAL) levels as a biomarker for the early diagnosis of heart failure patients without of kidney disease
This observational analysis evaluates NGAL levels as a potential biomarker for heart failure, suggesting diagnostic implications in patients without kidney disease.
Key Points
NGAL levels were significantly higher in heart failure patients than in healthy controls, indicating its potential diagnostic utility.
The study involved 118 participants, including 59 heart failure patients and 59 healthy controls, with NGAL correlating strongly with heart failure incidence.
Blood samples were collected to analyze multiple biomarkers, including NGAL, CRP, and cardiac troponin I, revealing significant differences.
Findings support NGAL's role as a valuable biomarker for identifying heart failure early in patients without a history of kidney issues.