September 10, 2025BMC GeriatricsOpen Access

Sex modifies the association between malnutrition and chronic kidney disease in community-dwelling older adults in the United States

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Discussion

Observational analysis finds malnutrition increases CKD risk in older adults, indicating sex modifies this association.

Malnutrition is significantly linked to a higher prevalence of chronic kidney disease in older adults.
The adjusted odds ratios indicate that moderate to severe malnutrition more than doubles the risk for CKD at 1.88.
Multivariable logistic regression was employed to assess the relationship between nutritional status and CKD.
Findings suggest that sex modifies the relationship between malnutrition and the prevalence of chronic kidney disease.

Zhang et al. (2025) studied this question.

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