Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Frontiers in PharmacologyOpen Access

Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota

View Full Paper
Ask AI
Bookmark
Share

Authors

WLWeiguang LvSHShengnan HanKLKe Li

Discussion

Loading...

Member takes

Overview

Observational analysis showed baicalein improves ulcerative colitis by reducing inflammation and modulating gut microbiota.

Key Points

  • Baicalein significantly improves ulcerative colitis symptoms, particularly at higher doses, reducing inflammation.
  • Key findings indicate that baicalein lowers pro-inflammatory cytokines like TNF-α and IL-1β while increasing IL-10.
  • The study used a DSS-induced murine model to assess protective effects against ulcerative colitis effectively.
  • These results highlight baicalein's potential as a novel treatment option for ulcerative colitis, warranting further exploration.

Cite This Study

Lv et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791c6chttps://doi.org/10.3389/fphar.2025.1564783
View Full Paper
Ask AI
Bookmark
Share