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September 10, 2025

Association of Infections with Relapse in Steroid Sensitive Nephrotic Syndrome in Children

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Authors

ATAndleeb TariqYZY. ZiaSHShamama Hasan

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Overview

Prospective analysis shows high relapse rates in children with SSNS linked to infections, suggesting a need for better management strategies.

Key Points

  • Infections significantly contribute to relapse in children with SSNS, with 79.6% experiencing relapse post-infection.
  • URTI and LRTI are the most common infections, affecting the relapse and remission outcomes in treated children.
  • The majority, 63.2%, achieved spontaneous remission, but those needing steroids showed higher diuretic use, indicating severe relapse.
  • Hypoalbuminemia was identified as a critical factor related to severe relapse requiring steroid treatment.

Cite This Study

Tariq et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791bcahttps://doi.org/10.61919/83mcja89
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Study of the Clinical Profile and Spectrum of Infections in Childhood Primary Nephrotic Syndrome2023
  2. 2Steroid response and outcomes in childhood nephrotic syndrome: A multicenter, cross-sectional study from Jordan2025
  3. 3Evaluation of Outcomes in Early Versus Late Steroid-resistant Nephrotic Syndrome in Children: An Observational Study2023
  4. 4Age correlation with childhood nephrotic syndrome2025
  5. 5Prevalence and Clinical Profile of Septic Acute Kidney Injury in Steroid Responsive Nephrotic Syndrome in a Tertiary Care Hospital in Eastern India: A Prospective Observational Study2025