This prospective observational study evaluates the correlation between anti-müllerian hormone and antral follicle count, highlighting their roles in ovarian reserve assessment.
Background: In general, anti-müllerian hormone (AMH) is positively associated with antral follicle count (AFC). AMH and AFC are correlated with the ovarian response, but their reliability and reproducibility are questionable. Methods: This is a prospective observational study. A total of 50 patients were selected who visited the hospital for infertility treatment. It was conducted in SKIMS MCH Srinagar over a period of 4 months from January 2023 to April 2023. Karl Pearson’s correlation coefficient was employed for assessing correlation between AMH levels and Total AFC. A P value of less than 0.05 was considered statistically significant. Results: Total of 50 patients were included in the study with mean age of patients being 34.1. The mean BMI of patients was 27.1 and mean duration of infertility was 3.6years. Mean±SD of AFC between age group 26 to 30 was 6.41±9.65 between 31 to 35 was 5.60±4.42 and between 36 to40 was 2.76±2.34, with a p value of 0.012 (statistically significant). Mean±SD of AMH between age 26 to30 was 2.10±1.98 between age 31to35 was 1.83±2.19 and between age 36 to40 was 0.49±0.72. Conclusion: AMH is considered as most reliable investigation for ovarian reserve testing. However, AFC can be used in place of AMH in poor patients as the cost of AMH is more as they have a strong corelation.
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Naseer et al. (2025) studied this question.