September 10, 2025Nutritional Neuroscience

Astaxanthin attenuates carrageenan-induced oxidative stress and inflammation in mice brain: possible role of the wnt/β-catenin signaling pathway

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Authors

SSSeyed Reza Mokhtari Sangdehi AMAkbar Hajizadeh Moghaddam SJSedigheh Khanjani Jelodar

Discussion

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Implication

Observational analysis shows astaxanthin attenuates inflammation and oxidative stress in mice, indicating involvement of wnt/β-catenin signaling pathway.

Key Points

Astaxanthin significantly reduced oxidative stress indicators, improving antioxidant enzyme activity and pain response.
Mice treated with astaxanthin showed lower levels of inflammatory markers like tnf-α and il-6, and higher levels of antioxidant enzymes.
This study utilized a mouse model of carrageenan-induced inflammation to assess the protective effects of astaxanthin.
Findings suggest astaxanthin's potential in modulating oxidative stress and inflammation, highlighting its therapeutic benefits.

Cite This Study

Sangdehi et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791379 https://doi.org/10.1080/1028415x.2025.2538052

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Implication

Observational analysis shows astaxanthin attenuates inflammation and oxidative stress in mice, indicating involvement of wnt/β-catenin signaling pathway.