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September 10, 2025Frontiers in MedicineOpen Access

Data-driven cluster analysis on the association of aging, obesity and insulin resistance with new-onset diabetes in Chinese adults: a multicenter retrospective cohort study

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Authors

YWYazhi WangMZMingkang ZhangPWPeng Wang

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Overview

Retrospective cohort study reveals significant links between aging, obesity, and insulin resistance for diabetes risk.

Key Points

  • Cluster analysis found distinct groups associated with varying diabetes incidence rates.
  • Subjects in Cluster 4 had the highest diabetes incidence, with significant risks noted across clusters.
  • Utilizing K-means clustering, five standardized indicators effectively identified high-risk populations.
  • Findings support targeted interventions for groups linked to aging, obesity, and insulin resistance.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d647911d7https://doi.org/10.3389/fmed.2025.1640017
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