September 10, 2025Frontiers in MedicineOpen Access

Case Report: Anaerococcus vaginalis spondylodiscitis diagnosed and cured based on nanopore targeted sequencing

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Authors

BZBing ZhouChinese Academy of Sciences YGYanghongxu GuoHunan University of Traditional Chinese Medicine BSBeiduo ShenShanghai East Hospital

Discussion

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Implication

Case report reveals effective treatment for spondylodiscitis in a patient with lumbar disc herniation, indicating novel insights from nanopore targeted sequencing.

Key Points

Prompt diagnosis enabled effective treatment of spondylodiscitis caused by anaerococcus vaginalis, leading to remarkable recovery.
Nanopore targeted sequencing successfully detected anaerococcus vaginalis despite negative culture results, underscoring its diagnostic importance.
Patient suffered worsened back pain due to lumbar disc herniation and spondylodiscitis but responded well to antibiotic therapy.
This case highlights a previously unreported cause of spondylodiscitis, emphasizing the need for awareness and further studies.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d6479117f https://doi.org/10.3389/fmed.2025.1645609

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Implication

Case report reveals effective treatment for spondylodiscitis in a patient with lumbar disc herniation, indicating novel insights from nanopore targeted sequencing.