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September 10, 2025Frontiers in PhysiologyOpen Access

Targeting atrial fibrillation in HFpEF: the emerging role of pulsed field ablation

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Authors

APAbdul Shokor ParwaniBKB KossmannVSVittorio Schweiger

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Overview

Observational analysis shows promising outcomes of pulsed field ablation in patients with atrial fibrillation and heart failure, highlighting its potential benefits.

Key Points

  • Pulsed field ablation appears to improve hemodynamics in patients with atrial fibrillation and heart failure.
  • Early clinical data suggest that pulsed field ablation leads to lower atrial fibrosis in heart failure patients.
  • Registry data supports early rhythm control strategies for managing atrial fibrillation in heart failure patients.
  • Continued trials, like CABA-HFpEF-DZHK27, aim to confirm the cardiovascular benefits of ablation in this patient group.

Cite This Study

Parwani et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d6479112chttps://doi.org/10.3389/fphys.2025.1621118
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulsed-Field Ablation in Atrial Fibrillation: A Paradigm Shift in Electrophysiology2025 · 2 citations
  2. 2Pulsed field ablation for atrial fibrillation: clinical applications and research advances2025
  3. 3Pulsed field ablation: focused on atrial fibrillation ablation2025
  4. 4Advent of Pulsed Field Ablation for Atrial Fibrillation: State-of-the-Art Review2025 · 4 citations
  5. 5Pulsed field ablation of atrial fibrillation in patients with reduced ejection fraction: an international, multicenter study2026