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September 10, 2025Current Topics in Medicinal Chemistry

Exploring Therapeutic Potential of Emblica officinalis (Amla) Against Streptozotocin-Induced Diabetic Nephropathy in Wistar Rats

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Authors

UYUmber YounasMKMuhammad Issa KhanIPImran Pasha

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Overview

Animal study evaluates amla's impact on diabetic nephropathy, suggesting significant improvements in renal biomarkers and oxidative stress.

Key Points

  • Amla supplementation improved renal function markers and reduced oxidative stress in rats with diabetic nephropathy.
  • HPLC analysis demonstrated high levels of vitamin C and quercetin in amla, supporting its therapeutic potential.
  • The 5% amla diet showed better results in managing blood glucose levels compared to the 7% diet, suggesting a dose-response relationship.
  • Findings indicate that amla targets inflammation and oxidative stress, mitigating diabetic nephropathy progression.

Cite This Study

Younas et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d64790f1chttps://doi.org/10.2174/0115680266387196250714050937
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