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September 10, 2025Journal of Medical EconomicsOpen Access

Comparison of enteral nutritional therapy to induce and maintain remission in paediatric patients with mild-to-moderate Crohn’s disease: a cost-effectiveness analysis in the UK

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Authors

MPMinal PatelRSRita Shergill-BonnerPSPreeti Sharma

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Overview

Cost-effectiveness analysis compares specialised formula to oral nutritional supplements in children, suggesting improved outcomes.

Key Points

  • Specialised formula saves £591 per patient annually while maintaining similar QALYs compared to standard ONS.
  • In a cohort of 1,000 patients, 552 achieved remission with specialised formula, compared to 496 with standard ONS.
  • Deterministic and probabilistic sensitivity analyses identified key drivers of cost-effectiveness, influencing treatment decisions.
  • Main limitation is the lack of clinical trials comparing specialised formula to standard ONS, suggesting a need for more research.

Cite This Study

Patel et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d64790ddehttps://doi.org/10.1080/13696998.2025.2539644
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Enteral Nutrition in Pediatric Crohn’s Disease: New Perspectives2025
  2. 2Cost–Utility Analysis of Treatment Sequences for Moderate-to-Severe Crohn’s Disease2025
  3. 3Understanding Patient and Physician Perspectives on Exclusive Enteral Nutrition in Adults with Crohn’s Disease: Bridging the Gap in Nutritional Therapy2025
  4. 4Using machine learning to predict clinical remission with exclusive enteral nutrition in pediatric Crohn disease2025
  5. 5Immunomodulators and Advanced Therapies for Induction of Remission in Crohn's Disease: A Systematic Review and Network Meta-Analysis.2025 · 6 citations