September 10, 2025Frontiers in MicrobiologyOpen Access

Gut microbiota in gastric cancer: from pathogenesis to precision medicine

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Discussion

Review highlights gut microbiota's impact on gastric cancer, indicating potential therapeutic and diagnostic strategies.

Gut microbiota plays a critical role in gastric cancer development, impacting immune response and inflammation.
Helicobacter pylori contributes significantly to tumorigenesis by generating reactive oxygen species and altering metabolic pathways.
Therapeutic strategies targeting gut microbiota, such as probiotics and fecal microbiota transplantation, show promise in cancer management.
Microbial biomarkers offer valuable insights for early diagnosis and personalized treatment of gastric cancer.

Huo et al. (2025) studied this question.

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