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September 10, 2025Journal of Thoracic DiseaseOpen Access

Short-term results of salvage surgery after immune and target therapies in non-small cell lung cancer

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Authors

MCMarco ChiappettaCSCarolina SassorossiFLFilippo Lococo

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Overview

Observational analysis highlights promising outcomes of salvage surgery in non-small cell lung cancer, suggesting potential in select patients post-therapy.

Key Points

  • Salvage surgery after target therapy or immunotherapy achieved a pathological complete response in 36% of patients.
  • Among 30 analyzed patients, complications occurred in 20%, and no peri-operative mortality was reported.
  • Most surgeries involved lobectomy/bilobectomy, with 22 patients initially contraindicated due to N2 involvement.
  • Median follow-up was 12 months, during which recurrence was observed in 5 patients, with 4 deaths recorded.

Cite This Study

Chiappetta et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d6479074fhttps://doi.org/10.21037/jtd-2025-387
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