September 10, 2025Journal of Thoracic DiseaseOpen Access

Key risk factors for mortality after pneumonectomy for lung cancer: insights from a large single-center cohort study

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Discussion

Retrospective analysis shows significant mortality rates in NSCLC patients after pneumonectomy, highlighting critical risk factors.

The 30-day and 90-day mortality rates after pneumonectomy for lung cancer were 4.3% and 9.1%, respectively.
Significant risk factors for early mortality included bronchopleural fistula, positive bronchial resection margin, and prolonged intubation.
The study analyzed a cohort of 514 patients who underwent pneumonectomy for non-small cell lung cancer from 2006 to 2020.
A follow-up of 90 days post-surgery is crucial to accurately assess short-term mortality rates after lung resections.

Skrzypczak et al. (2025) studied this question.

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