Maternal Serum Concentrations of Per- and Polyfluoroalkyl Substances and Gestational Weight Gain: A Systematic Review and Meta-analysis

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Discussion

Meta-analysis reveals no significant link between PFAS levels and gestational weight gain, suggesting further research is needed.

No significant association was found between PFAS levels and gestational weight gain.
In women with pre-pregnancy BMI ≤25, PFNA was the only substance positively correlated with weight gain.
The meta-analysis included various studies and adhered to PRISMA guidelines to ensure quality.
Calls for further research emphasize the need for larger cohort studies to clarify these associations.

Halili et al. (2025) studied this question.

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