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September 10, 2025Russian Journal of Pediatric Hematology and OncologyOpen Access

Polycythemia vera in children: a literature review

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Authors

ABA. V. BogdanovАPА. V. Pshonkin

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Overview

Literature review analyzes polycythemia vera's impact on children, highlighting risks and treatment limitations.

Key Points

  • Polycythemia vera is rarely diagnosed in children, with an incidence of 0.18 per 100,000 person-years.
  • Only 50% of young patients show symptoms related to polycythemia, often leading to accidental diagnosis.
  • The JAK2 gene mutation is part of the diagnostic criteria, but its prevalence in children is significantly lower than in adults.
  • No general treatment algorithm for pediatric polycythemia vera exists, reflecting limited data on cytoreductive therapy outcomes.

Cite This Study

Bogdanov et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d6478fdc2https://doi.org/10.21682/2311-1267-2024-11-4-71-80
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Application of polycythemia vera guidelines in pediatric patient with erythrocytosis: A case series2025
  2. 2Polycythemia Vera – A Myeloproliferative Disorder2025
  3. 3Estimating incidence and prevalence of polycythemia vera and associated eligibility for cytoreductive therapies in major US health plans2025
  4. 4Integrating clinical features, long-term Outcomes and NGS-based mutational analysis in AYA patients with essential Thrombocythemia and polycythemia vera: A Multicenter Retrosepective study2025
  5. 5Clinicopathological characteristics and outcome of patients with Philadelphia negative myeloproliferative neoplasms: first report from Upper Egypt2025