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September 10, 2025Neurosurgery

Neurological Outcomes and the Role of Timing in the Surgical Management of Patients With Cervical Spinal Cord Injury Without Fracture and Dislocation: Systematic Review and Meta-Analysis

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Authors

ADAsimina DominariGMGiorgos D. MichalopoulosSISufyan Ibrahim

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Overview

Systematic review shows high neurological improvement in cervical spinal cord injury after surgery, indicating timing may not significantly impact outcomes.

Key Points

  • High rates of neurological improvement were observed in surgically treated patients for cervical spinal cord injury without fracture.
  • Postoperative neurological improvement was noted in 62% of patients who had surgery within 72 hours of injury, showing similar outcomes regardless of timing.
  • The analysis included 16 studies involving 398 patients and assessed improvement through a random-effects model meta-analysis.
  • Findings suggest that timings of surgery might not significantly differ in rates of neurological recovery among patients with cervical spinal cord injury.

Cite This Study

Dominari et al. (2025) studied this question.

synapsesocial.com/papers/68c23dc5b210217d6478f44dhttps://doi.org/10.1227/neu.0000000000003665
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating the role of surgical timing on clinical outcomes in traumatic spinal cord injury: A systematic review and meta-analysis2025
  2. 2The impact of early vs. delayed surgery on outcomes in cervical spinal cord injury without fracture or dislocation2025
  3. 3The race against time: patterns and variables of spine surgery timing in traumatic spinal cord injury: a retrospective cohort study from the TraumaRegister DGU®2025 · 1 citations
  4. 4Non-traumatic Spinal Cord Injury2025
  5. 5Comparison of Clinical Outcomes between Surgical and Conservative Treatments for Cervical Spinal Cord Injury without Fracture and Dislocation2025