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September 10, 2025JAMA Network OpenOpen Access

Sex-Related Measurement Bias in Autism Spectrum Disorder Symptoms in the Baby Siblings Research Consortium

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Authors

CBCatherine A. BurrowsUniversity of MinnesotaSSSooyeon SungUniversity of MinnesotaSZShuting ZhengUniversity of North Carolina at Chapel Hill

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Implication

Cohort study uncovers measurement bias in autism spectrum disorder symptoms by gender, suggesting improvement for earlier identification.

Key Points

  • Measurement bias was identified in autism spectrum disorder symptoms, with females rated less impaired compared to males.
  • In the high familial likelihood group, females showed fewer difficulties in eye contact and social communication traits.
  • Cohort study utilized longitudinal data from the Baby Siblings Research Consortium to analyze symptom differences by sex.
  • Findings suggest that diagnostic criteria should consider sex differences to enhance early identification of ASD in females.

Cite This Study

Burrows et al. (2025) studied this question.

synapsesocial.com/papers/68c23dc5b210217d6478f350https://doi.org/10.1001/jamanetworkopen.2025.25887
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