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September 10, 2025Tikrit Journal of Veterinary Sciences

Dose-dependent cytotoxicity effect of Aspirin on MCF7 cell line proliferation

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Authors

HHHadeel HusseinSWSiham Agmee Wadee

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Overview

Observational analysis shows dose-dependent cytotoxicity of aspirin in MCF7 cells, suggesting potential anticancer applications.

Key Points

  • Aspirin reduced the growth and viability of MCF7 cells, resulting in a significant apoptotic effect.
  • The IC50 for aspirin was determined to be 465 µg/ml, with growth inhibition highest at 35.5% for 1000 µg/ml concentration.
  • Cytotoxicity was assessed using the MTT assay to measure cell proliferation and viability with varying aspirin doses.
  • These findings highlight aspirin's potential as an anticancer agent, though further clinical studies are needed.

Cite This Study

Hussein et al. (2023) studied this question.

synapsesocial.com/papers/68c23dc5b210217d6478ebe8https://doi.org/10.25130/tjvs.1.2.4
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