Observational analysis reveals significant differences in liver function tests between hepatitis B and C in pregnant women, indicating important biochemical variations.
Liver inflammation is called hepatitis, which can go away on its own or get worse and turn into cirrhosis, fibrosis, or liver cancer. Liver function tests explore serious liver diseases progression and their impact, like viral hepatitis. Aspartate and ALT, are frequently elevated and discharged into the bloodstream following a hepatitis infection. The study's objective was to determine the levels of liver enzymes and IL 6 in pregnant women with hepatitis C and B virus groups at various stages of the illness. Blood samples were collected from 40 pregnant women infected with hepatitis who visited Baghdad Medical Hospital in Baghdad Governorate / Iraq for use in determining HBsAg, HCV, ALT, AST, ALP, Direct Bilirubin, and IL-6. The study result shows there are significant differences (P≤0.05) between the pregnant women with hepatitis B and C in the study samples; the number of pregnant women suffering from HBV in the studied group was 39 (65%) in comparison with the number of pregnant women suffering from HCV 21 patient (35 %). In our research, Total blood bilirubin (TSB) levels and liver enzymes were found to be significantly different (P≤0.05) between pregnant women with hepatitis B and C in this study. There were also big changes in the levels of AST. The average AST for HBV was 19.90 ± 5.77, while 26.64 ± 5.11 for HCV. No big differences were found in the ALT or ALP levels, and IL-6 levels were not significantly different between the viral types, with a negative correlation. We conclude that there are significant differences in certain biochemical parameters between pregnant women infected with hepatitis B and C. Specifically, TSB and AST levels were notably higher in HCV patients.
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M. Abbas (2024) studied this question.