Preclinical Evidence forPeltophorum PterocarpumExtracts AndPure Compound In Pain And Inflammation Models Along With In-Vitro Antioxidant And Acute Toxicity Assessment To Validate Its Traditional Uses.
Preclinical analysis reveals analgesic and anti-inflammatory effects of peltophorum pterocarpum in rodents, highlighting bergenin's potential as a natural therapy.
Key Points
The study revealed significant analgesic and anti-inflammatory effects from peltophorum pterocarpum extracts in rodent models without observed toxicity.
In vivo tests demonstrated a strong dose-dependent response with both the hexane extract and the isolated compound bergenin showing promising potential.
Antioxidant activity was assessed using the FRAP assay, confirming the traditional uses of the plant for various medicinal applications.
The findings support the development of bergenin as a safe natural analgesic and anti-inflammatory agent, enhancing its therapeutic relevance.