This framework demonstrates pulsatile blood flow in vascular networks in the cerebral cortex, suggesting implications for hypertension and hemodynamics.
Key Points
An innovative framework modeled pial vascularization, enabling efficient blood flow simulations in the cerebral cortex.
The framework integrated patient-specific geometry with over 75,000 vessels, highlighting extensive network complexity.
One-dimensional simulations revealed significant differences in pulsatility index values between normotensive and hypertensive states.
Large pressure gradients in terminal vessels indicate crucial regional variations, potentially impacting cerebral health.