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September 10, 2025CureusOpen Access

Bacteriological Profile and Antimicrobial Resistance Patterns in Neonatal Sepsis: Special Reference to Klebsiella pneumoniae at a Tertiary Care Hospital in Eastern India

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Authors

BSBiyanka SauSGSrijita GhoshSMS. Mal

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Overview

This prospective cross-sectional study assesses resistance patterns of Klebsiella pneumoniae in neonatal sepsis, highlighting urgent actions needed.

Key Points

  • Multidrug-resistant Klebsiella pneumoniae was identified in 93.75% of all cases of neonatal sepsis.
  • Culture positivity rate observed was 66%, with Klebsiella pneumoniae being the predominant pathogen at 16%.
  • Blood cultures were performed in a prospective cross-sectional study involving 100 neonates suspected of sepsis.
  • This highlights the critical need for antibiotic stewardship and effective infection control practices in neonatal settings.

Cite This Study

Sau et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478e14ehttps://doi.org/10.7759/cureus.91735
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical and Microbiological Profile of Culture-Positive Neonatal Sepsis in a Tertiary Care Center in North India2025 · 2 citations
  2. 2BACTERIOLOGICAL PROFILE OF NEONATAL SEPTICEMIA AND ANTIBIOTIC SUSCEPTIBILITY PATTERN OF THE ISOLATES IN TERTIARY CARE HOSPITAL2025 · 1 citations
  3. 3Pattern and trend of bacterial resistance in neonatal sepsis in infants admitted to the neonatal intensive care unit, from 2016 to 20212025
  4. 4Maternal Health and Antibiotic Resistance: Klebsiella pneumoniae Isolates Analysis2025
  5. 5ANTIBIOTIC SUSCEPTIBILITY TRENDS AMONG KLEBSIELLA PNEUMONIAE ISOLATES IN CLINICAL SPECIMENS AT A TERTIARY CARE HOSPITAL2025