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September 10, 2025British Journal of Dermatology

Primary Cutaneous CD4+ Small Medium T Cell Lymphoproliferative Disorder – 20 years of experience from a specialist centre

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Authors

SBSophie BashallBTBjorn ThomasVSVan Sim

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Implication

Service evaluation reveals treatment variation and survival outcomes in 86 patients with PCSM-TLPD, suggesting effective management strategies.

Key Points

  • PCSM-TLPD shows a 100% disease-specific survival rate, and those with solitary lesions have an excellent prognosis.
  • Patients with multiple lesions had a significantly higher relapse rate of 63%, compared to 4% in those with solitary lesions.
  • The study identified variations in treatment approaches, with topical steroids and low-dose radiotherapy being common strategies.
  • Staging scans confirmed no systemic disease in 100% of cases, indicating they may no longer be necessary for these patients.

Cite This Study

Bashall et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478e135https://doi.org/10.1093/bjd/ljaf338
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