Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025

Metabolic Reprogramming: A Crucial Contributor to Anticancer Drug Resistance.

View Full Paper
Ask AI
Bookmark
Share

Authors

YZYanchang ZhuWYWeijie YanLTLingfeng Tong

Discussion

Loading...

Member takes

Overview

Review discusses how metabolic alterations in the tumor microenvironment contribute to drug resistance, suggesting potential therapeutic strategies.

Key Points

  • Metabolic reprogramming significantly contributes to anticancer drug resistance, complicating treatment effectiveness.
  • Altered glucose, lipid, and amino acid metabolism in tumor cells and their microenvironment create barriers to chemotherapy.
  • The review summarizes recent advancements in targeting metabolic changes to overcome drug resistance in cancer therapy.
  • Understanding upstream regulatory mechanisms in cancer metabolism may open avenues for developing efficient treatment strategies.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478df91https://doi.org/10.1002/mco2.70358
View Full Paper
Ask AI
Bookmark
Share