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September 10, 2025

Genetics of Sudden Cardiac Arrest: Overview of Genetic Risk Factors and Aetiologies.

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Authors

STSarah Ming Li TanSLShir Lynn LimMOMarcus Eng Hock Ong

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Overview

This review highlights genetic risk factors and polygenic inheritance contributing to sudden cardiac death.

Key Points

  • Understanding genetic factors in sudden cardiac death may improve risk stratification and prevention.
  • Coronary artery disease is the leading cause of sudden cardiac death in older individuals over 35.
  • Inherited cardiomyopathies and channelopathies are more prevalent causes of sudden cardiac death in younger individuals.
  • Polygenic inheritance suggests that multiple genetic variants contribute to the risk of sudden cardiac death.

Cite This Study

Tan et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478df03https://doi.org/10.15420/aer.2025.11
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