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September 10, 2025Acta Biochimica Iranica

Evaluating the Incidence, Risk Factors, and Diagnostic Limitations of Transient Neonatal Tyrosinemia in Iranian Newborns

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Authors

SASaeideh AbdolahpourMNMaryam NasriFAFarzaneh Abbasi

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Overview

Retrospective study assesses incidence of transient neonatal tyrosinemia in newborns, suggesting links to prematurity and cesarean delivery.

Key Points

  • The incidence of transient neonatal tyrosinemia in Iranian newborns is 0.47%, indicating significant health monitoring needs.
  • Logistic regression analysis reveals strong associations with prematurity (OR: 868.2) and cesarean delivery (OR: 3.5), demonstrating critical risk factors.
  • Data was analyzed from metabolic screening of 73,349 infants over four years, providing a comprehensive view of transient neonatal tyrosinemia cases.
  • Optimizing screening and encouraging vaginal delivery could help reduce transient neonatal tyrosinemia rates, highlighting perinatal care improvements.

Cite This Study

Abdolahpour et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478d7d3https://doi.org/10.18502/abi.v3i2.19487
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