September 10, 2025Current Cancer Drug Targets

Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice

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Resveratrol-chitosan nanoparticles significantly reduced tumor weight and volume in DMBA-induced breast cancer mice, enhancing treatment efficacy.
High entrapment efficiency (82.46%) and specific particle size (184.60 nm) of resveratrol-chitosan nanoparticles were established through various characterizations.
The study highlights the potential of resveratrol-chitosan nanoparticles as both radiosensitizers and tumor suppressors, regulating critical gene expressions.
Modulation of pro-inflammatory and antioxidant pathways indicates the nanoparticles may play a significant role in cancer therapy, warranting further research.

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Implication

This study demonstrates that resveratrol-chitosan nanoparticles improve tumor response to γ-irradiation in a breast cancer model, suggesting a dual therapeutic role.

Cite This Study

Hussein et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478d73a https://doi.org/10.2174/0115680096364549250828062651

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Implication

This study demonstrates that resveratrol-chitosan nanoparticles improve tumor response to γ-irradiation in a breast cancer model, suggesting a dual therapeutic role.

Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice

Key Points

Discussion

Implication

Cite This Study

Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice

Key Points

Discussion

Implication

Cite This Study

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